The TRIO gene is a vital component of human biology, playing a crucial role in various physiological processes, including neuronal development, cell migration, and cell signaling pathways. If you are seeking reliable and comprehensive information about the TRIO gene, several open sources can provide valuable insights into its functions, genetic variations, associated disorders, and ongoing research. Here after few resources.

1. The National Center for Biotechnology Information (NCBI) databases, such as Gene, PubMed, and ClinVar, offer a wealth of freely accessible information on the TRIO gene.

• NCBI GENE provides extensive details ranging from gene variants and protein products to reference sequences and relevant articles.

• PubMed compiles scientific literature on TRIO gene function and associated disorders.

• ClinVar specifically focuses on genetic variations and their clinical significance.

• GeneReviews provides curated genetic information and clinical insights on a vast array of genetic disorders.

2. OMIM also known as Online Mendelian Inheritance in Man, stands as a tool for medical geneticists, researchers, and healthcare professionals around the world. Researchers and geneticists can readily access information regarding specific genes, their functions, and how mutations and variations within these genes contribute to disease development.

• TRIPLE FUNCTIONAL DOMAIN; TRIO

• INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL DOMINANT 44, WITH MICROCEPHALY; MRD44

• INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL DOMINANT 63, WITH MACROCEPHALY; MRD63

3. ORPHANET is a comprehensive online resource that provides complete and reliable information about rare diseases and orphan drugs. It serves as a valuable tool for patients, researchers, healthcare professionals, and policymakers seeking to understand and address the complex challenges associated with rare diseases.

• TRIO Rho guanine nucleotide exchange factor TRIO

• Micrognathia recurrent infections behavioral abnormalities mild intellectual disability syndrome

4. GENECARDS is a highly informative and comprehensive database that provides description for each gene. This resource offers a quick glimpse into the functional significance and characteristics of various genes, enabling researchers and scientists to efficiently assess their potential roles in biological processes or disease mechanisms.

• TRIO Gene - GeneCards

5. VARSOME is a comprehensive online platform that offers variant interpretation and analysis solutions, empowering researchers and clinicians with accurate and efficient genomics information. With its user-friendly interface and extensive database, Varsome streamlines the process of variant analysis, supporting personalized medicine and advancing genetic research.

• TRIO | Gene (varsome.com)

6. The SFARI GENE database collects genetic data on autism spectrum disorders (ASD) from various studies, including humans and animals. It includes genome-wide association studies, copy-number variation analyses, and gene expression studies. These datasets help identify genes related to ASD. SFARI GENE categorizes genes based on their level of evidence, ranging from syndromic genes to high-confidence, strong, and suggestive genes. This categorization helps researchers prioritize their investigations. The database also provides detailed gene information, aiding researchers in understanding ASD mechanisms and identifying treatment targets.

• Gene: TRIO - (sfari.org)